ea0086p325 | Metabolism, Obesity and Diabetes | SFEBES2022
Sneha Kumar Sambhavi
, Wallis Natalie
, Sivakanthan Thiviya
, Raffan Eleanor
Background: Obesity is a global health concern and a recognised risk factor for several prevalent diseases. Genetic variation can influence susceptibility to the development of obesity. Existing work in humans explains a limited proportion of the heritability of obesity-related traits and prioritisation of variants on which to focus mechanistic studies is challenging. Novel insights can be obtained from species such as the domestic dog and the pig in which obesity occurs spont...